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PMEDAP
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Catalog No. T38514Cas No. 113852-41-8
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and mortality, as well as a human immunodeficiency virus (HIV) replication inhibitor with anti-murine cytomegalovirus (MCMV) activity.
PMEDAP
🥰Excellent
Purity: 98.12%
Catalog No. T38514Cas No. 113852-41-8
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and mortality, as well as a human immunodeficiency virus (HIV) replication inhibitor with anti-murine cytomegalovirus (MCMV) activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $29 | In Stock | |
| 2 mg | $42 | In Stock | |
| 5 mg | $68 | In Stock | |
| 10 mg | $107 | In Stock | |
| 25 mg | $238 | In Stock | |
| 50 mg | $381 | In Stock | |
| 100 mg | $573 | In Stock | |
| 200 mg | $779 | In Stock |
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CitedSelect Batch
Purity:98.12%
Contact us for more batch information
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and mortality, as well as a human immunodeficiency virus (HIV) replication inhibitor with anti-murine cytomegalovirus (MCMV) activity. |
| In vivo | In Three-week-old male NMRI mice inoculated with MSV, PMEDAP (0.25-5 mg/kg; IP; daily;) effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice. PMEDAP also suppressed tumor formation and mortality in a dose-dependent manner[2]. |
| Molecular Weight | 288.2 |
| Formula | C8H13N6O4P |
| Cas No. | 113852-41-8 |
| Smiles | C(COCP(=O)(O)O)N1C=2C(N=C1)=C(N)N=C(N)N2 |
| Relative Density. | 2.03 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | 0.1 M NaOH: 14.29 mg/mL (49.58 mM), when pH is adjusted to 12 with NaOH. Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
0.1 M NaOH
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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