Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $80 | In Stock | |
10 mg | $128 | In Stock | |
25 mg | $263 | In Stock | |
50 mg | $422 | In Stock | |
100 mg | $613 | In Stock |
Description | Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2, and dopamine receptors.Spiroxatrine may be used in the study of disorders related to the cardiovascular system. |
In vitro | Sproxatrine (0.01-0.1 μM, 15 mins) enhances contraction in the vas deferens tissue of α2A/D-adrenergic receptor knockout mice[2]. |
In vivo | Sproxatrine (1-25 μg, intraperitoneal injection, 5 days) increases withdrawal latency to thermal and mechanical stimuli in the hind paw of nerve-injured rats and carrageenan-induced inflammatory rats[3]. Sproxatrine (4 mg/kg/day, intraperitoneal injection, 5 minutes) enhances the effect of Fluoxetine in reducing selectively bred alcohol-preferring (P) rat's voluntary oral ethanol intake[3]. |
Alias | R 5188 |
Molecular Weight | 379.45 |
Formula | C22H25N3O3 |
Cas No. | 1054-88-2 |
Storage | store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble) |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.