Home Tools
Log in
Cart

Thiacloprid

Catalog No. T38272   CAS 111988-49-9

Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Thiacloprid Chemical Structure
Thiacloprid, CAS 111988-49-9
Pack Size Availability Price/USD Quantity
50 mg In stock $ 39.00
100 mg In stock $ 56.00
Bulk Inquiry
Get quote
Select Batch  
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.
Targets&IC50 α4β2 nAChR:2.7 nM(Drosophilan), α4β2 nAChR:860 nM(M10 mouse fibroblast cells)
Molecular Weight 252.72
Formula C10H9ClN4S
CAS No. 111988-49-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Methanol: Slightly soluble

Chloroform: Slightly soluble

TargetMolReferences and Literature

1. Tomizawa, M., and Casida, J.E.Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptorsAnnu. Rev. Entomol.48339-364(2003) 2. Verebová V, Želonková K, Holečková B, Staničová J. The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA. Physiol Res. 2019;68(Suppl 4):S459-S466. 3. Schuld, M., et al. Effects of Thiacloprid, a New Chloronicotinyl Insecticide, On the Egg Parasitoid Trichogramma cacaoeciae. Ecotoxicology 9, 197–205 (2000).

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Human Metabolite Library Anti-Parasitic Compound Library Neuronal Signaling Compound Library Bioactive Compounds Library Max Neurotransmitter Receptor Compound Library

Related Products

Related compounds with same targets
Dimethindene Tropicamide TZ3O Physostigmine Salicylate Catharanthine sulfate 4-Hydroxycoumarin Tribendimidine PNU-282987

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Thiacloprid 111988-49-9 Microbiology/Virology Neuroscience AChR Parasite damage pest Inhibitor cytotoxic insecticide inhibit vegetables DNA inhibitor

 

TargetMol