insecticide

Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy. No information is available on the reproductive, developmental, or carcinogenic effects of propoxur in humans. Mixed results are available from cancer studies of propoxur in animals. EPA has not classified propoxur for carcinogenicity.

2-Chloronaphthoquinone (2-Chloro-1,4-naphthoquinone) is a substituted naphthoquinone which is used as an insecticide and acaricide.

λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system.

Fenpyroximate is an acaricide and insecticide. It blocking the mitochondrial electron transport in complex I.

Diflubenzuron (Larvakil) is a benzoyl-urea insecticide, found to be a potent inhibitor of melanosome synthesis in mouse melanoma cells. Diflubenzuron has also been shown to inhibit TCDD-induced CYP1A1 expression in HepG2 cells.

3-Phenylpropanal (Phenylpropyl aldehyde) is a RIFM flavor ingredient and can be used to make perfume.3-Phenylpropanal is the main ingredient in acaricides.3-Phenylpropanal can be used as a fly attractant.3-Phenylpropanal can be used as an insecticide.

Adenosine receptor A1 antagonist 5 acts as an adenosine antagonist, is an oxypurine, acts as an insecticide and pest control agent, and has an inhibitory effect on elevated blood pressure.

Hydramethylnon (AC217300) is an insecticide primarily. Hydramethylnon is used for fire ants.

Itaconic anhydride (ITA) is a biobased material that is obtained from renewable resources. It is widely used in metal adhesion promoter, synthetic resin improver, esterification agent, herbicide, insecticide.

Transfluthrin is a volatile pyrethroid insecticide that targets insect voltage-gated sodium channels (VGSC).

RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) is a novel Insect growth regulator that can be used as a potential insecticide to control olive fruit fly.

N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline (KM1954) is an insecticide, it is most active against 1st stage Ae. aegypti larvae with LC50 values of 125μM.

Alodan (Nodon) is an organic chloride insecticide.

Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its administration in rats has been observed to induce the development of hepatocellular tumors.

Dehydroemetine is an effective antigenic insecticide, which is a synthetic analogue of Emetine dihydrochloride. It can be used to prevent and treat amoeba infections and diseases. It has the effect of treating leishmania infection with skin damage and resistance to metronidazole amoebiosis.

Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]

Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests including cockroaches, silverfish, ants, and fleas.

Imidacloprid is a systemic chloronicotinyl insecticide, which can be effectively used in agriculture to control pests .

Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.

Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225 nM for M. domestica GABACls and Gl

Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.

Avermectin B1 is served as anthelmintic and insecticide.

Chlorantraniliprole (Rynaxypyr) is an insecticide. Chlorantraniliprole potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).

2,3,4,5-Tetrachlorophenol is a metabolite of the insecticide γ-lindane.1It is toxic to fathead minnows and rainbow trout (LC50s = 0.496 and 0.304 mg/L, respectively, in tank water).2 1.Chadwick, R.W., and Freal, J.J.The identification of five unreported lindane metabolites recovered from rat urineBull. Environ. Contam. Toxicol.7(2)137-146(1972) 2.Holcombe, G.W., Phipps, G.L., Knuth, L., et al.The acute toxicity of selected substituted phenols, benzenes and benzoic acid esters to fathead minnows Pimephales promelasEnviron. Pollut.35(4)367-381(1984)

Diethyl fumarate is a decomposition product of the pesticide Malathion. Diethyl fumarate causes nonimmune contact urticaria on the skin.

Isobutylparaben is a preservative and preservative insecticide.

Cyantraniliprole D3 is deuterium-labeled Cyantraniliprole, which is a Ryan-like insecticide.

Clothianidin (TI 435), an insecticide, acts as an agonist of acetylcholine to stimulate nAChR, thereby activating post-synaptic acetylcholine receptors but not inhibiting AChE.

Flucythrinate is an insecticide.

Esfenvalerate (Asana) is a widely used insecticide.

(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)

Endosulfan sulfate is a highly toxic and persistent compound that serves as the primary metabolite of the insecticide Endosulfan, which is extensively utilized for various crops.

Metam-sodium is an organic sodium salt and organosulfur insecticide that appears as a yellow to light yellow-green solution with varying strengths of amine and sulfur odors. It can be used as a herbicide, insecticide, fungicide and pesticide.

Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa, etc., in a concentration-dependent manner.

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.

Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.

Flupyradifurone, a systemic nicotinic acetylcholine receptor (nAChR) agonist, disrupts signal transduction within the central nervous system of sucking pests, functioning as a butenolide insecticide [1].

Cismethrin is a pyrethroid insecticide.

Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.

Japonilure is an agent of insecticide and pheromone.

Celangulin XIX, an insecticide derived from Celastrus angulatus, exhibits potent activity against Mythimna separata, with an effective dose (ED50) of 73.3 μg/g [1].

Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 against adult spider mites, spider mite eggs, and C. elegans are reported at IC50 values of 5.3, 41.1, and 9.5 μg/ml.

Azothoate is an insecticide agent.

Methiocarb, a carbamate pesticide, is used as an insecticide, acaricide, bird repellent, and molluscicide. Methiocarb stimulates cholinergic by inhibiting reversibly acetylcholinesterase activity, making methiocarb a potent neurotoxin.

Benoxafos, HOE 2910, is an insecticide.

Endosulfan I is an organochlorine insecticide and a stereoisomer of endosulfan II . It is active against a variety of insects, including bollworms (LD50 = 0.63 mg/g). Endosulfan I binds to GABA receptors in rat brain membranes with an IC50 value of 30 nM and is toxic to rats (LD50 = 18 mg/kg).

Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediated by the activation of conventional

Niloticin is a mosquito insecticide from Limonia acidissima L.

Fenoxycarb (Insegar) is an insecticide against mosquitoes.