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Acetamiprid

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Purity:99.78%

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COA HNMR HPLC

Acetamiprid

Catalog No. T14094Cas No. 135410-20-7

Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders.

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Pack Size	Price	Availability
50 mg	$41	In Stock
100 mg	$59	In Stock
500 mg	$143	In Stock
1 mL x 10 mM (in DMSO)	$66	In Stock

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Product Introduction

Bioactivity

Description

In vivo

Acetamiprid decreases in body weight and mildly affected spermatogenesis [1]. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats[2]. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice[1].

Chemical Properties

Molecular Weight	222.67
Formula	C10H11ClN4
Cas No.	135410-20-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 97 mg/mL (435.62mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4910 mL	22.4548 mL	44.9095 mL	224.5475 mL
5 mM	0.8982 mL	4.4910 mL	8.9819 mL	44.9095 mL
10 mM	0.4491 mL	2.2455 mL	4.4910 mL	22.4548 mL
20 mM	0.2245 mL	1.1227 mL	2.2455 mL	11.2274 mL
50 mM	0.0898 mL	0.4491 mL	0.8982 mL	4.4910 mL
100 mM	0.0449 mL	0.2245 mL	0.4491 mL	2.2455 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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