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Sulfoxaflor
Catalog No. T19940Cas No. 946578-00-3
Alias XDE 208, GF 2372, GF 2032
Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid.
Sulfoxaflor
Catalog No. T19940Alias XDE 208, GF 2372, GF 2032Cas No. 946578-00-3
Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $113 | In Stock | |
| 5 mg | $322 | In Stock | |
| 10 mg | $479 | In Stock | |
| 25 mg | $768 | In Stock | |
| 50 mg | $1,050 | In Stock | |
| 100 mg | $1,390 | In Stock |
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Purity:99.87%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid. |
| In vitro | METHODS: Blood lymphocytes were treated with Sulfoxaflor (GF 2032) (10 µg/mL, 20 µg/mL, 40 µg/mL), and single cell gel electrophoresis (comet electrophoresis), cytokinesis block micronucleus assay (MN assay), flow cytometry, and catalase (CAT) enzyme activity measurement were used to determine genotoxicity, apoptotic effects, and oxidative damage potential, respectively. RESULTS CPBI values and the number of viable cells decreased; the number of late apoptotic and necrotic cells, micronucleus frequency, and comet assay parameters (GDI and DCP) increased; an increase in CAT enzyme levels was observed at 10 and 20 µg/mL concentrations, and CAT enzyme activity was inhibited at 40 µg/mL. [3] |
| In vivo | METHODS: Sulfoxaflor (GF 2032) (25, 100, and 500 mg/kg, gavage, 4 weeks) was administered to rats and the relative testicular mass, testosterone, FSH, LH, MDA, and GPx levels, sperm motility, sperm morphology, sperm DNA damage, and histopathological changes in the testis, epididymis, and seminal vesicle were examined. RESULTS Sulfoxaflor exposure resulted in an increase in FSH, LH, MDA, and GPx levels in sperm, as well as the percentage of dead and abnormal sperm and DNA damage in rat sperm. [2] |
| Alias | XDE 208, GF 2372, GF 2032 |
| Molecular Weight | 277.27 |
| Formula | C10H10F3N3OS |
| Cas No. | 946578-00-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (199.09 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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