sulfoximine

DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent and specific glutamylcysteine synthetase biosynthesis inhibitor.

L-Methionine-DL-sulfoximine (MSO) inhibits glutamine synthetase and metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine can be used in convulsant studies.

Methionine sulfoximine (MSO) is an irreversible glutamine synthetase inhibitor. It is the sulfoximine derivative of methionine with convulsant effects.

L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.

L-Buthionine-(S,R)-sulfoximine hydrochloride is a potent, cell-permeable, fast-acting and irreversible inhibitor of G-glutamylcysteine synthetase (γ-GCS) and depletes cellular glutathione levels. L-Buthionine-(S,R)-sulfoximine has IC50s of 1.9 μM, 8.6 μM, and 29 μM in melanoma, breast and ovarian tumor specimens, respectively [1] [2].

DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.

(S)-Ceralasertib is a potent and selective inhibitor of sulfoximine morpholinopyrimidine ATR with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. .

Sulfoxaflor (GF 2032), an agonist of nAChR1 and nAChR2 subtypes, is a systemic insecticide that acts on the central nervous system of insects. Sulfoxaflor is used for the control of sap-feeding insects such as Nilaparvata lugens, Bemissia tabaci, Myzus persicae, an