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Tolazoline hydrochloride
🥰Excellent
Catalog No. T1680Cas No. 59-97-2
Alias Tolazoline HCl, NSC35110 (hydrochloride), Imidaline hydrochloride, Imidaline (hydrochloride), Benzidazol hydrochloride
Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.
Tolazoline hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T1680Alias Tolazoline HCl, NSC35110 (hydrochloride), Imidaline hydrochloride, Imidaline (hydrochloride), Benzidazol hydrochlorideCas No. 59-97-2
Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 g | $40 | In Stock | |
| 5 g | $92 | In Stock | |
| 10 g | $133 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $43 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn. |
| In vivo | In cases of persistent pulmonary hypertension of the newborn (PPHN), Tolazoline acts as a pulmonary vasodilator, effectively reducing pulmonary vascular resistance (PVR) and pulmonary arterial pressure. Additionally, within the human radial artery, Tolazoline blocks α-adrenergic activity, significantly counteracting vascular spasms. |
| Alias | Tolazoline HCl, NSC35110 (hydrochloride), Imidaline hydrochloride, Imidaline (hydrochloride), Benzidazol hydrochloride |
| Molecular Weight | 196.68 |
| Formula | C10H13ClN2 |
| Cas No. | 59-97-2 |
| Smiles | Cl.C(C1=NCCN1)c1ccccc1 |
| Relative Density. | 1.09g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 36 mg/mL (183 mM) DMSO: 55 mg/mL (279.64 mM)  Ethanol: 37 mg/mL (188.1 mM) | |||||||||||||||||||||||||||||||||||
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H2O/Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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