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Xylometazoline hydrochloride
🥰Excellent
Catalog No. T0042Cas No. 1218-35-5
Alias Xylometazoline HCl
Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.
Xylometazoline hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T0042Alias Xylometazoline HClCas No. 1218-35-5
Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 g | $30 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant. |
| Targets&IC50 | α1B-adrenoceptor:560 nM, α1A-adrenoceptor:80 nM, α2A-adrenoceptor:980 nM, α2C-adrenoceptor:220 nM, α1D-adrenoceptor:450 nM |
| In vitro | Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. Xylometazoline binds at adrenoceptor subtypeα1A, α1B, α1D, α2A, α2B, α2C with IC50 of 0.08, 0.56, 0.45, 0.98, 1.8, 0.22 μM, repectively. [1] |
| Alias | Xylometazoline HCl |
| Molecular Weight | 280.84 |
| Formula | C16H24N2·HCl |
| Cas No. | 1218-35-5 |
| Smiles | Cl.Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 16 mg/mL (56.97 mM), Sonication is recommended.  Ethanol: 52 mg/mL (185.2 mM) H2O: 51 mg/mL (181.6 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O/Ethanol
H2O/Ethanol
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
α2C-adrenergic receptorα2B-adrenergic receptorα2A-adrenergic receptorα1D-adrenergic receptorα1B-adrenergic receptorα1A-adrenergic receptorXylometazoline hydrochlorideXylometazoline HydrochlorideXylometazolinerunny nosenose stuffinessInhibitorinhibitincrease nasal airflowconstrict nasal blood vesselsBeta ReceptorAdrenergicReceptorAdrenergic Receptor
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