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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $39 | In Stock | |
2 mg | $58 | In Stock | |
5 mg | $97 | In Stock | |
10 mg | $148 | In Stock | |
25 mg | $253 | In Stock | |
50 mg | $371 | In Stock | |
100 mg | $520 | In Stock | |
500 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $107 | In Stock |
Description | (R)-Terazosin is an active R-enantiomer of Terazosin and a potent antagonist of α1-adrenoceptor [(α1a, α1b, and α1d-adrenoceptor] with Ki values of 6.51 nM, 1.01 nM, and 1.97 nM, respectively). |
Targets&IC50 | α1A-adrenoceptor:6.51 nM (Ki), α1B-adrenoceptor:1.01 nM (Ki), α1D-adrenoceptor:1.97 nM (Ki) |
In vitro | (R)-Terazosin exhibits low affinity for α2a, α2B, and α2c-adrenoceptors (Ki of 3.85 μM, 0.33 μM, and 0.37 μM, respectively). It may serve as a useful probe for exploring the functional roles of adrenoceptor subtypes in various tissues. |
In vivo | (R)-Terazosin demonstrates antagonism at rat atrial α2B receptor (pEC30: 5.69) and at rat vas deferens α1A and α2A receptors (pA2: 7.5 and 5.31, respectively). |
Molecular Weight | 387.43 |
Formula | C19H25N5O4 |
Cas No. | 109351-34-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (141.96 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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