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(Rac)-Idroxioleic acid

Catalog No. T16075Cas No. 56472-29-8
Alias Minerval, 2-OHOA, 2-Hydroxyoleic acid

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.

(Rac)-Idroxioleic acid

(Rac)-Idroxioleic acid

Catalog No. T16075Alias Minerval, 2-OHOA, 2-Hydroxyoleic acidCas No. 56472-29-8
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$106In Stock
10 mg$172In Stock
25 mg$355In Stock
50 mg$569In Stock
1 mL x 10 mM (in DMSO)$175In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.
Targets&IC50
Jurkat cells:40 μM
In vitro
Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1].
In vivo
In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1].
AliasMinerval, 2-OHOA, 2-Hydroxyoleic acid
Chemical Properties
Molecular Weight298.46
FormulaC18H34O3
Cas No.56472-29-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (167.52 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3505 mL16.7527 mL33.5053 mL167.5266 mL
5 mM0.6701 mL3.3505 mL6.7011 mL33.5053 mL
10 mM0.3351 mL1.6753 mL3.3505 mL16.7527 mL
20 mM0.1675 mL0.8376 mL1.6753 mL8.3763 mL
50 mM0.0670 mL0.3351 mL0.6701 mL3.3505 mL
100 mM0.0335 mL0.1675 mL0.3351 mL1.6753 mL

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