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(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $52 | In Stock | |
5 mg | $106 | In Stock | |
10 mg | $172 | In Stock | |
25 mg | $355 | In Stock | |
50 mg | $569 | In Stock | |
1 mL x 10 mM (in DMSO) | $175 | In Stock |
Description | (Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization. |
Targets&IC50 | Jurkat cells:40 μM |
In vitro | Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1]. |
In vivo | In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1]. |
Alias | Minerval, 2-OHOA, 2-Hydroxyoleic acid |
Molecular Weight | 298.46 |
Formula | C18H34O3 |
Cas No. | 56472-29-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (167.52 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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