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(Rac)-WAY-161503

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Purity:98.08%

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COA HNMR HPLC

(Rac)-WAY-161503

Catalog No. T13332Cas No. 75704-24-4

(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.

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Pack Size	Price	Availability
5 mg	$86	In Stock
10 mg	$119	In Stock
25 mg	$192	In Stock
50 mg	$280	In Stock
100 mg	$415	In Stock

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Product Introduction

Bioactivity

Description	(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.
In vivo	In male C57BL/6J mice, (Rac)-WAY-161503 (3-30 mg/kg; i.p.) treatment dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082. Additionally, in the 5-HT2A KO mice, the decreased locomotor activity produced by 10 mg/kg DOI is potentiated [1].

Chemical Properties

Molecular Weight	272.13
Formula	C11H11Cl2N3O
Cas No.	75704-24-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90 mg/mL (330.7 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6747 mL	18.3736 mL	36.7471 mL	183.7357 mL
5 mM	0.7349 mL	3.6747 mL	7.3494 mL	36.7471 mL
10 mM	0.3675 mL	1.8374 mL	3.6747 mL	18.3736 mL
20 mM	0.1837 mL	0.9187 mL	1.8374 mL	9.1868 mL
50 mM	0.0735 mL	0.3675 mL	0.7349 mL	3.6747 mL
100 mM	0.0367 mL	0.1837 mL	0.3675 mL	1.8374 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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