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Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-

Catalog No. T9129Cas No. 63476-70-0

Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- is an inhibitor of p53 with an IC50 value of 0.35 μM

Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-

Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-

Purity: 98.97%
Catalog No. T9129Cas No. 63476-70-0
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- is an inhibitor of p53 with an IC50 value of 0.35 μM
Pack SizePriceAvailabilityQuantity
1 mg$74In Stock
5 mg$182In Stock
10 mg$268In Stock
25 mg$457In Stock
50 mg$656In Stock
100 mg$919In Stock
500 mg$1,830In Stock
1 mL x 10 mM (in DMSO)$188In Stock
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Purity:98.97%
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Product Introduction

Bioactivity
Description
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- is an inhibitor of p53 with an IC50 value of 0.35 μM
Targets&IC50
p53:0.35 μM
Chemical Properties
Molecular Weight324.38
FormulaC22H16N2O
Cas No.63476-70-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 11 mg/mL (33.91 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0828 mL15.4140 mL30.8280 mL154.1402 mL
5 mM0.6166 mL3.0828 mL6.1656 mL30.8280 mL
10 mM0.3083 mL1.5414 mL3.0828 mL15.4140 mL
20 mM0.1541 mL0.7707 mL1.5414 mL7.7070 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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