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ABBV-744

ABBV-744
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
Catalog No. T4697Cas No. 2138861-99-9
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Purity:100%
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ABBV-744

Catalog No. T4697Cas No. 2138861-99-9
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
2 mg$54In Stock
5 mg$97In Stock
10 mg$153In Stock
25 mg$315In Stock
50 mg$455In Stock
100 mg$555In Stock
200 mg$798In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Product Introduction

Bioactivity
Description
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
Targets&IC50
BRD4 BD2:3 nM (Kd), BRD3 BD2:13 nM (IC50), BRD4 BD2:4 nM (IC50), BRD2 BD2:8 nM (IC50), BRDT BD2:18 nM (IC50)
AliasABBV744
Chemical Properties
Molecular Weight491.55
FormulaC28H30FN3O4
Cas No.2138861-99-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (91.54 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0344 mL10.1719 mL20.3438 mL101.7191 mL
5 mM0.4069 mL2.0344 mL4.0688 mL20.3438 mL
10 mM0.2034 mL1.0172 mL2.0344 mL10.1719 mL
20 mM0.1017 mL0.5086 mL1.0172 mL5.0860 mL
50 mM0.0407 mL0.2034 mL0.4069 mL2.0344 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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