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Alogliptin

Catalog No. T6192Cas No. 850649-61-5
Alias SYR-322

Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.

Alogliptin

Alogliptin

Purity: 99.63%
Catalog No. T6192Alias SYR-322Cas No. 850649-61-5
Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
2 mg$44In Stock
5 mg$72In Stock
10 mg$113In Stock
25 mg$228In Stock
50 mg$347In Stock
100 mg$522In Stock
500 mg$1,120In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Purity:99.63%
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Product Introduction

Bioactivity
Description
Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
Targets&IC50
DPP4:<10 nM
AliasSYR-322
Chemical Properties
Molecular Weight339.39
FormulaC18H21N5O2
Cas No.850649-61-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 68 mg/mL (200.35 mM)
H2O: 2 mg/mL (5.89 mM)
Ethanol: 60 mg/mL (176.8 mM)
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.9465 mL14.7323 mL29.4646 mL147.3231 mL
5 mM0.5893 mL2.9465 mL5.8929 mL29.4646 mL
Ethanol/DMSO
1mg5mg10mg50mg
10 mM0.2946 mL1.4732 mL2.9465 mL14.7323 mL
20 mM0.1473 mL0.7366 mL1.4732 mL7.3662 mL
50 mM0.0589 mL0.2946 mL0.5893 mL2.9465 mL
100 mM0.0295 mL0.1473 mL0.2946 mL1.4732 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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