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Fipronil

Catalog No. T2196 CAS 120068-37-3

Synonyms: Fluocyanobenpyrazole, Termidor

Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Fipronil, CAS 120068-37-3

Pack Size	Availability	Price/USD
25 mg	In stock	$ 39.00
50 mg	In stock	$ 64.00
100 mg	In stock	$ 97.00
200 mg	In stock	$ 137.00
500 mg	In stock	$ 213.00
1 mL * 10 mM (in DMSO)	In stock	$ 43.00

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Purity: 97.48%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Fluocyanobenpyrazole, Termidor
Molecular Weight	437.15
Formula	C12H4Cl2F6N4OS
CAS No.	120068-37-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (102.94 mM)

References and Literature

1. Zaluski R, et al. Environ Toxicol Chem. 2015 May;34(5):1062-9. 2. Wang K, Li B, Yu Y, et al. Bacterial Rdl2 dsRNA increased the insecticidal activity of GABAR blockers and allosteric modulators against Plutella xylostella[J]. bioRxiv. 2021

Citations

1. Li B J, Wang K K, Yu Y, et al.PxRdl2 dsRNA increased the insecticidal activities of GABAR-targeting compounds against Plutella xylostella.Pesticide Biochemistry and Physiology.2023: 105548.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Neurodegenerative Disease Compound Library Membrane Protein-targeted Compound Library Anti-Alzheimer's Disease Compound Library Bioactive Compound Library Target-Focused Phenotypic Screening Library Neurotransmitter Receptor Compound Library Fluorochemical Library Neuronal Signaling Compound Library Human Metabolite Library

Related Products

Related compounds with same targets

CYP1B1-IN-5 α-Terpinyl acetate Cephaeline dihydrochloride XL388 Demethyleneberberine N-desmethyl Olanzapine Liarozole Ticagrelor

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Fipronil 120068-37-3 Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience P450 GluCls GABA Receptor γ-Aminobutyric acid Receptor Inhibitor CYPs Fluocyanobenpyrazole Termidor Gamma-aminobutyric acid Receptor inhibit Cytochrome P450 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.