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By Target- GABA Receptor
- GluCls(1)
- P450(1)
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Search Result
Results for "
fipronil
" in TargetMol Product Catalog- Inhibitors & Agonists3
Fipronil
Cited
Fluocyanobenpyrazole,Termidor
T2196120068-37-3
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
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CitedFipronil sulfone
T21071120068-36-2
Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.
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Flufiprole
Rizazole,Butene-fipronil
T25428704886-18-0
Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.
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