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Fluconazole

Catalog No. T1388   CAS 86386-73-4
Synonyms: UK-49858

Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Fluconazole Chemical Structure
Fluconazole, CAS 86386-73-4
Pack Size Availability Price/USD Quantity
50 mg In stock $ 36.00
100 mg In stock $ 48.00
200 mg In stock $ 59.00
500 mg In stock $ 72.00
1 mL * 10 mM (in DMSO) In stock $ 30.00
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Purity: 99.17%
Purity: 97.77%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
Synonyms UK-49858
Molecular Weight 306.27
Formula C13H12F2N6O
CAS No. 86386-73-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 30.6 mg/mL (100 mM)

DMSO: 30.6 mg/mL (100 mM)

TargetMolReferences and Literature

1. Uppuluri P, et al. Antimicrob Agents Chemother, 2008, 52(3), 1127-1132. 2. Rogers TE, et al. Antimicrob Agents Chemother, 1986, 30(3), 418-422. 3. Chin NX, et al. Antimicrob Agents Chemother, 1997, 41(4), 850-852. 4. Larsen RA, et al. Antimicrob Agents Chemother, 1996, 40(9), 2178-2182. 5. Kuang Y, Chai Y, Xu L, et al. Glabrone as a specific UGT1A9 probe substrate and its application in discovering the inhibitor glycycoumarin[J]. European Journal of Pharmaceutical Sciences. 2021: 105786. 6. Tsang C C, Chan K F, Chan W, et al. Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing[J]. Emerging Microbes & Infections. 2020: 1-53. 7. Tsang C C, Tang J Y M, Chan K F, et al. Diversity of phenotypically non-dermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing[J]. Emerging microbes & infections. 2019;8(1):531-541.

TargetMolCitations

1. Ma L, Lian Y, Tang J, et al. Identification of the Anti-Fungal Drug Fenticonazole Nitrate as a Novel PPARγ-Modulating Ligand With Good Therapeutic Index: Structure-Based Screening and Biological Validation. Pharmacological Research. 2021: 105860. 2. Tsang C C, Tang J Y M, Chan K F, et al. Diversity of phenotypically non-dermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing. Emerging Microbes & Infections. 2019, 8(1): 531-541 3. Ren L, Li W, Zheng X, et al. Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle. Acta Pharmacologica Sinica. 2021: 1-15. 4. Tsang C C, Chan K F, Chan W, et al. Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing. Emerging Microbes & Infections. 2021 Dec;10(1):81-96. 5. Kuang Y, Chai Y, Xu L, et al. Glabrone as a specific UGT1A9 probe substrate and its application in discovering the inhibitor glycycoumarin. European Journal of Pharmaceutical Sciences. 2021: 105786.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Microbial Natural Product Library Anti-Cancer Active Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Human Metabolite Library Anti-Metabolism Disease Compound Library CNS-Penetrant Compound Library Anti-Cancer Compound Library Orally Active Compound Library

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Fluconazole 86386-73-4 Microbiology/Virology Antibiotic Antifection Antifungal Agent Inhibitor albicans UK49858 UK-49858 Fungal fungi,Candida kefyr Triazole Candida C. albicans UK 49858 inhibit inhibitor

 

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