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Fosravuconazole L-lysine ethanolate
Catalog No. T8847Cas No. 914361-45-8
Alias E-1224 L-lysine ethanolate, BMS-379224 L-lysine ethanolate
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent approved in Japan for treating onychomycosis, a fungal nail infection. It is a prodrug converted into ravuconazole.
Fosravuconazole L-lysine ethanolate
Catalog No. T8847Alias E-1224 L-lysine ethanolate, BMS-379224 L-lysine ethanolateCas No. 914361-45-8
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent approved in Japan for treating onychomycosis, a fungal nail infection. It is a prodrug converted into ravuconazole.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $32 | In Stock | |
| 5 mg | $46 | In Stock | |
| 10 mg | $73 | In Stock | |
| 25 mg | $143 | In Stock | |
| 50 mg | $227 | In Stock | |
| 100 mg | $373 | In Stock | |
| 200 mg | $527 | In Stock |
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Purity:95%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent approved in Japan for treating onychomycosis, a fungal nail infection. It is a prodrug converted into ravuconazole. |
| In vitro | Fosravuconazole exhibits potent in vitro antifungal activity against a broad spectrum of fungal species, including Candida, Aspergillus, and Trichophyton species [1]. |
| In vivo | Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) suppresses parasitemia and prevents death in mice infected with the T. cruzi Y strain[2]. |
| Alias | E-1224 L-lysine ethanolate, BMS-379224 L-lysine ethanolate |
| Molecular Weight | 739.7 |
| Formula | C31H40F2N7O8PS |
| Cas No. | 914361-45-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 48 mg/mL (64.89 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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