Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 52.00 | |
50 mg | In stock | $ 84.00 | |
100 mg | In stock | $ 137.00 | |
200 mg | In stock | $ 218.00 | |
500 mg | In stock | $ 462.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. |
Targets&IC50 | mouse SGLT2:5.64 nM, hSGLT2:7.4 nM, rat SGLT2:6.73 nM |
Kinase Assay | Inhibition of TNF-α synthesis: TNF-α inhibitory activity is measured in lipopolysacharide (LPS) stimulated PBMC. Pomalidomide is added to human PBMCs 1 hour prior to the addition of LPS (1 μg/mL) and incubation continued for an additional 18-20 hours. Supernatants are then harvested, and the concentration of TNF-α in the supernatants is determined by ELISA. The concentration of Pomalidomide that inhibits TNF- production by 50% (IC50) is calculated by nonlinear regression analysis. The human whole blood TNF- inhibition assay is run in a similar fashion to the PBMC assay except that heparinized fresh human whole blood is plated directly into microtiter plates. |
Synonyms | ASP1941 |
Molecular Weight | 404.45 |
Formula | C21H21FO5S |
CAS No. | 761423-87-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 70 mg/mL (173.07 mM)
You can also refer to dose conversion for different animals. More
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Ipragliflozin 761423-87-4 GPCR/G Protein SGLT Inhibitor ASP1941 ASP 1941 Sodium-dependent glucose cotransporters inhibit ASP-1941 inhibitor