Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 122.00 | |
5 mg | In stock | $ 239.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 623.00 | |
50 mg | In stock | $ 888.00 | |
100 mg | In stock | $ 1,220.00 |
Description | LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. |
In vitro | LMP744 (0.1-5 μM, 3 days) induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle[2].The GI50 value of LMP744 for NCI60 cells is 0.1 μM[2]. |
In vivo | LMP744 ?(10-50 mg/kg) administered i.v. push once a week for 4 weeks in nude mice moderately actives against human A253 and FaDu tumor xenografts without significant toxicity[1]. |
Synonyms | NSC706744 hydrochloride, MJ-III65 hydrochloride |
Molecular Weight | 488.92 |
Formula | C24H25ClN2O7 |
CAS No. | 308246-57-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.56 mg/mL (11.37 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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