Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 572.00 | |
100 mg | In stock | $ 822.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors. |
In vitro | Loreclezole, at concentrations above 6 microM, enhanced the degree and rate of apparent desensitization of the whole-cell current in a concentration-dependent manner [1]. The action of loreclezole depends on the type of beta subunit present in the receptor complex; receptors containing beta 2 or beta 3 subunits have > 300-fold higher affinity for loreclezole than receptors containing a beta 1 subunit [2]. |
Molecular Weight | 274.53 |
Formula | C10H6Cl3N3 |
CAS No. | 117857-45-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (327.83 mM)
You can also refer to dose conversion for different animals. More
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Loreclezole 117857-45-1 Membrane transporter/Ion channel Neuroscience GABA Receptor γ-Aminobutyric acid Receptor R 72063 Inhibitor Gamma-aminobutyric acid Receptor R72063 R-72063 inhibit inhibitor