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Medifoxamine

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Purity:98.35%

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COA HNMR HPLC LCMS

Medifoxamine

Catalog No. T24444Cas No. 32359-34-5

Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine preferentially inhibits dopamine reuptake.

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Pack Size	Price	Availability
1 mg	$116	In Stock
5 mg	$289	In Stock
10 mg	$478	In Stock
25 mg	$737	In Stock
50 mg	$987	In Stock
100 mg	$1,380	In Stock
500 mg	$2,790	In Stock
1 mL x 10 mM (in DMSO)	$318	In Stock

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Product Introduction

Bioactivity

Description	Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine preferentially inhibits dopamine reuptake.
In vivo	Medifoxamine (200, 500, 750, and 1000 mg; oral) was well tolerated and exhibited a first-order linear pharmacokinetic profile. It underwent rapid absorption and peak plasma concentrations were achieved about 1.0 h after administration. Thereafter the elimination profile was biphasic with a mean terminal half-life less than 3 hours. We found a linear relationship (r = 0.80) between administered dose and AUC values for the four doses. High values were obtained for the apparent volumes of distribution and the plasma clearance.[4]
Alias	LG 152, Medifoxamina, LG-152, LG152

Chemical Properties

Molecular Weight	257.33
Formula	C16H19NO2
Cas No.	32359-34-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90.0 mg/mL (349.7 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8861 mL	19.4303 mL	38.8606 mL	194.3030 mL
5 mM	0.7772 mL	3.8861 mL	7.7721 mL	38.8606 mL
10 mM	0.3886 mL	1.9430 mL	3.8861 mL	19.4303 mL
20 mM	0.1943 mL	0.9715 mL	1.9430 mL	9.7152 mL
50 mM	0.0777 mL	0.3886 mL	0.7772 mL	3.8861 mL
100 mM	0.0389 mL	0.1943 mL	0.3886 mL	1.9430 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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