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Methyldopa hydrate

Catalog No. T5954 CAS 41372-08-1

Synonyms: Alpha-Methyldopa Sesquihydrate, L-(-)-α-Methyldopa hydrate, MK-351 hydrate, Methyldopa Sesquihydrate

Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.

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Methyldopa hydrate, CAS 41372-08-1

Pack Size	Availability	Price/USD
500 mg	In stock	$ 41.00
1 g	In stock	$ 48.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Biological Description

Chemical Properties

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Description

Synonyms	Alpha-Methyldopa Sesquihydrate, L-(-)-α-Methyldopa hydrate, MK-351 hydrate, Methyldopa Sesquihydrate
Molecular Weight	238.24
Formula	C10H13NO4·3/2H2O
CAS No.	41372-08-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33.33 mg/mL (139.90 mM)

References and Literature

1. Baila M R , Cintas J A . [The use of the combination of L-alpha-methyldopa and dichlorothiazide in the treatment of arterial hypertension][J]. El Día Médico, 1962, 34:2422. 2. Program N T . NTP Toxicology and Carcinogenesis Studies of alpha-Methyldopa Sesquihydrate (CAS No. 41372-08-1) in F344/N Rats and B6C3F1 Mice (Feed Studies).[J]. National Toxicology Program Technical Report, 1989, 348.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Inhibitor Library GPCR Compound Library Clinical Compound Library Anti-Parkinson's Disease Compound Library FDA-Approved Drug Library

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Related compounds with same targets

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Keywords

Methyldopa hydrate 41372-08-1 GPCR/G Protein Neuroscience Dopamine Receptor Adrenergic Receptor L-α-Methyldopa Hydrate MK351 Hydrate Methyldopa MK351 metabolized prodrug MK 351 Methyldopa Hydrate Alpha-Methyldopa Sesquihydrate α-Methyldopa Sesquihydrate hyperglycemic L-(-)-α-Methyldopa hydrate L-alpha-Methyldopa Hydrate L-a-Methyldopa Hydrate Beta Receptor MK-351 hydrate Methyldopa Sesquihydrate antihyoertensive response MK-351 MK 351 Hydrate Inhibitor a-Methyldopa Sesquihydrate MK-351 Hydrate inhibit inhibitor

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