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Methyldopa hydrate
🥰Excellent
Catalog No. T5954Cas No. 41372-08-1
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
Methyldopa hydrate
🥰Excellent
Catalog No. T5954Cas No. 41372-08-1
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $41 | In Stock | |
| 1 g | $48 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $45 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity. |
| Molecular Weight | 238.24 |
| Formula | C10H13NO4·3/2H2O |
| Cas No. | 41372-08-1 |
| Smiles | O.C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 12 mg/mL (50.37 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
α-Methyldopa SesquihydrateresponseprodrugMK351 HydrateMK-351MK351MK 351 HydrateMK 351MethyldopametabolizedL-α-Methyldopa HydrateL-a-Methyldopa HydrateL-alpha-Methyldopa HydratehyperglycemicDopamineReceptorDopamine Receptorantihyoertensivea-Methyldopa SesquihydrateAdrenergicReceptorAdrenergic Receptor
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