Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NL-1 is a mitoNEET inhibitor with antileukemic effect.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 61.00 | |
25 mg | In stock | $ 126.00 | |
50 mg | In stock | $ 216.00 | |
100 mg | In stock | $ 324.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 41.00 |
Description | NL-1 is a mitoNEET inhibitor with antileukemic effect. |
In vitro | NL-1 Reduced the number of viable cells in REH, REH/Ara-C and ALL (SUP-B15, TOM-1, JM1, NALM-1, NALM-6, BV-173) cell lines, in a concentration-dependent manner. |
In vivo | NL-1 showed antileukemic activity in an in vivo mouse ALL model |
Cell Research | Cell Line:REH, REH/Ara-C and ALL (SUP-B15, TOM-1, JM1, NALM-1, NALM-6, BV-173) cell lines. Concentration:10 μM, 20 μM, 30 μM, 40 μM, 50 μM, 60 μM, 70 μM, 80 μM, 100 μM.Incubation Time:72 hours |
Animal Research | Animal Model:10 female NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice (6-8 month old) injected with TOM-1 ALL cells. Dosage:10 mg/kg.Administration:Intraperitoneal injection; daily; for 5 days |
Molecular Weight | 335.46 |
Formula | C18H25NO3S |
CAS No. | 188532-26-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (745.25 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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NL-1 188532-26-5 Autophagy Metabolism Mitochondrial Metabolism Inhibitor viability leukemia CISD1 antileukemic MitoNEET NL 1 lymphoblastic inhibit B-Cell acute anti-cancer NL1 inhibitor