Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
2 mg | In stock | $ 147.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 463.00 | |
25 mg | In stock | $ 763.00 | |
50 mg | In stock | $ 1,070.00 | |
100 mg | In stock | $ 1,430.00 | |
500 mg | In stock | $ 2,890.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 367.00 |
Description | 1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated. |
Targets&IC50 | Na+, K+-ATPase:620 nM (IC50) |
Source |
Synonyms | Neriostene, Folinerin, Foliandrin |
Molecular Weight | 576.72 |
Formula | C32H48O9 |
CAS No. | 465-16-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
Pyridine, Methanol, etc.: Soluble
DMSO: 60 mg/ml (104.04 mM)
You can also refer to dose conversion for different animals. More
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Oleandrin 465-16-7 Apoptosis Membrane transporter/Ion channel Potassium Channel ATPase Sodium Channel Neriostene PBI-05204 Folinerin Na+/K+ ATPase PBI 05204 Inhibitor PBI05204 Sodium potassium pump Foliandrin inhibit inhibitor