1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
8-Hydroxydigitoxigenin is a natural product of Nerium, Apocynaceae. The catalog number is TN5291 and the CAS number is 1049674-06-7. 8-Hydroxydigitoxigenin can be used as a reference standard.
β-Anhydrouzarigenin is a natural product of Nerium, Apocynaceae. The catalog number is TN5290 and the CAS number is 3080-20-4. β-Anhydrouzarigenin can be used as a reference standard.
Dehydroadynerigenin beta-neritrioside is a natural product for research related to life sciences. The catalog number is TN3793 and the CAS number is 143212-60-6.
Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.
17alpha-Neriifolin and 17alpha-Deacetyltanghinin have little anti-proliferative activity, indicating that the 17beta configuration is critical for the anti-proliferative activity of these compounds.
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarciclasine is provided, this antitumor agent has an advantage of having an excellent therapeutic effect of tumor and less side effects.
Dehydroadynerigenin glucosyldigitaloside is a natural product for research related to life sciences. The catalog number is TN3792 and the CAS number is 144223-70-1.
Cardenolide B-1 is a natural product of Nerium, Apocynaceae. The catalog number is TN3595 and the CAS number is 1318158-89-2. Cardenolide B-1 can be used as a reference standard.
Dehydroadynerigenin digitaloside is a natural product for research related to life sciences. The catalog number is TN3791 and the CAS number is 52628-62-3.