Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to affecting the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway. chemical and concentration-dependent. Trachelogenin has antiviral, anti-inflammatory and analgesic activities with IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively.
Nortrachelogenin-8'-O-beta-glucoside is a lignan with a diarylhydroxybutyrolactone skeleton which isolated from the leaves and stems of Trachelospermum jasminoides (Lindl.) Lem.
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).
Nortracheloside is a natural product of Trachelospermum, Apocynaceae. The catalog number is TMA1065 and the CAS number is 33464-78-7. Nortracheloside can be used as a reference standard.
Nortrachelogenin-5'-C-beta-glucoside is a natural product of Trachelospermum, Apocynaceae. The catalog number is TN6509 and the CAS number is 858127-39-6. Nortrachelogenin-5'-C-beta-glucoside can be used as a reference standard.