Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
2,6-Dimethylbenzoquinone (2,6-Dimethylquinone) is a benzoquinone, a chemical compound found in Rauvolfia vomitoria and in Tibouchina pulchra.At physiological concentrations 2, 6-Dimethoxy-p-benzoquinone is an antibacterial substance
A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity.
Vellosimine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN5224 and the CAS number is 6874-98-2. Vellosimine can be used as a reference standard.
3-Hydroxysarpagine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2953 and the CAS number is 857297-90-6. 3-Hydroxysarpagine can be used as a reference standard.
Perakine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2051 and the CAS number is 4382-56-3. Perakine can be used as a reference standard.
10-Hydroxy-16-epiaffinine, a natural product of Rauvolfia (Apocynaceae), has the catalog number TN6039 and the CAS number 82513-70-0. It can be used as a reference standard.
Antirhine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN3425 and the CAS number is 16049-28-8. Antirhine can be used as a reference standard.
10-Hydroxydihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2568 and the CAS number is 451478-47-0. 10-Hydroxydihydroperaksine can be used as a reference standard.
Raucaffricine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN4894 and the CAS number is 31282-07-2. Raucaffricine can be used as a reference standard.
Dihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN3860 and the CAS number is 16100-84-8. Dihydroperaksine can be used as a reference standard.
Vinorine is a direct biosynthetic precursor along the complex pathway to the monoterpenoid indole alkaloid ajmaline, an antiarrhythmic drug from the Indian medicinal plant Rauvolfia serpentina.
Akuammidine shows anti-inflammatory and anti-asthmatic properties, it has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively.
Peraksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN6030 and the CAS number is 15527-80-7. Peraksine can be used as a reference standard.