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Phenytoin

Catalog No. T0939 CAS 57-41-0

Synonyms: 5,5-Diphenylhydantoin, Diphenylhydantoin

Purity 99.95% Datasheet MSDS

Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.

Phenytoin, CAS 57-41-0

Pack Size	Availability	Price/USD
100 mg	In stock	35.00
200 mg	In stock	42.00
500 mg	In stock	50.00
1 g	In stock	59.00
1 mL * 10 mM (in DMSO)	In stock	54.00

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Purity 99.95%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Targets&IC50

Sodium Channel,

Synonyms	5,5-Diphenylhydantoin , Diphenylhydantoin
Purity	99.95%
Appearance	solid
Molecular Weight	252.27
Formula	C15H12N2O2
CAS No.	57-41-0

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 47 mg/mL (186.3 mM)

Ethanol: 11 mg/mL (43.6 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Owoeye O, et al. J Diet Suppl. 2015 Mar;12(1):105-17.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Neuronal Signaling Compound Library Ion Channel Inhibitor Library FDA-approved Drug Library Anti-Cardiovascular Disease Compound Library CNS-Penetrant Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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