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Phenytoin

Catalog No. T0939Cas No. 57-41-0
Alias Diphenylhydantoin, 5,5-Diphenylhydantoin

Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. It potentially acts by promoting sodium efflux from neurons in the motor cortex, reducing post-tetanic potentiation at synapses. This prevents cortical seizure foci from spreading to adjacent areas and stabilizes the threshold against hyperexcitability. Additionally, it appears to reduce muscle spindle sensitivity to stretch, causing muscle relaxation.

Phenytoin

Phenytoin

Purity: 99.95%
Catalog No. T0939Alias Diphenylhydantoin, 5,5-DiphenylhydantoinCas No. 57-41-0
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. It potentially acts by promoting sodium efflux from neurons in the motor cortex, reducing post-tetanic potentiation at synapses. This prevents cortical seizure foci from spreading to adjacent areas and stabilizes the threshold against hyperexcitability. Additionally, it appears to reduce muscle spindle sensitivity to stretch, causing muscle relaxation.
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1 g$50In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.95%
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Product Introduction

Bioactivity
Description
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. It potentially acts by promoting sodium efflux from neurons in the motor cortex, reducing post-tetanic potentiation at synapses. This prevents cortical seizure foci from spreading to adjacent areas and stabilizes the threshold against hyperexcitability. Additionally, it appears to reduce muscle spindle sensitivity to stretch, causing muscle relaxation.
AliasDiphenylhydantoin, 5,5-Diphenylhydantoin
Chemical Properties
Molecular Weight252.27
FormulaC15H12N2O2
Cas No.57-41-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 11 mg/mL (43.6 mM)
DMSO: 55 mg/mL (218.02 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.9640 mL19.8200 mL39.6401 mL198.2003 mL
5 mM0.7928 mL3.9640 mL7.9280 mL39.6401 mL
10 mM0.3964 mL1.9820 mL3.9640 mL19.8200 mL
20 mM0.1982 mL0.9910 mL1.9820 mL9.9100 mL
DMSO
1mg5mg10mg50mg
50 mM0.0793 mL0.3964 mL0.7928 mL3.9640 mL
100 mM0.0396 mL0.1982 mL0.3964 mL1.9820 mL

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