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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm. |
Alias | Pyquiton, Droncit, Biltricide |
Molecular Weight | 312.41 |
Formula | C19H24N2O2 |
Cas No. | 55268-74-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 70 mg/mL (224.06 mM), Sonication is recommended. Ethanol: 59 mg/mL (188.8 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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