Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
Description | Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases. |
In vitro | Mechanism of Silymarin involves different biochemical reactions, such as stimulation of the rate of ribosomal RNA synthesis by stimulating the transcription of polymerase I and ribosomal RNA genes, blockage of alpha-glycoside loops toxin intake, and protection of cell membranes from free radical-induced damage. Silymarin also displays a substantial protective effect against UVB-induced canceration at different stages, possibly through its strong antioxidant properties. |
In vivo | The intravenous injection LD50 of Silymarin is 391.4 mg/kg, 70.1 mg/kg, 142.3 mg/kg for mice, rats, rabbits, respectively. |
Synonyms | Silybin B, 水飞蓟素 |
Molecular Weight | 482.441 |
Formula | C25H22O10 |
CAS No. | 65666-07-1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 97 mg/mL (201.06 mM)
H2O: <1 mg/mL
Ethanol: 1 mg/mL (2.07 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Silymarin 65666-07-1 微生物学 SARS-CoV thistle angiogenesis Inhibitor hepatocellular resistance SARS coronavirus chemopreventive inhibit HCC Milk insulin proliferation carcinoma Silybin B inhibitor