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Sulfadoxine

Catalog No. T0836   CAS 2447-57-6
Synonyms: Sulphadoxine

Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.

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Sulfadoxine Chemical Structure
Sulfadoxine, CAS 2447-57-6
Pack Size Availability Price/USD Quantity
500 mg In stock $ 41.00
1 mL * 10 mM (in DMSO) In stock $ 45.00
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Purity: 98.36%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.
Kinase Assay Competitive binding assays: Cells are harvested from 150-sq cm T-flasks, and cytosol is prepared at a protein concentration of approximately 2 mg/mL in phosphate buffer. Aliquots of this 180,000 ×g supernatant are then incubated with various concentrations of Tamoxifen and 2.5 nM [3H]estradiol for 16 hr at 0-4 ℃. The free steroids are absorbed by dextran-charcoal [l0 μL of 0.5% Dextran C-5% Norite A in TE buffer] for 1 hr at 0 ℃, and aliquots are counted after centrifugation at 800 ×g, 30 min. The relative binding ability of each competitor is taken as the ratio of the concentration of radioinert estradiol/competitor required to inhibit one-half of the specific [3H]estradiol binding, with the affinity of estradiol set at 100%.
Synonyms Sulphadoxine
Molecular Weight 310.33
Formula C12H14N4O4S
CAS No. 2447-57-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 57 mg/mL (183.7 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

TargetMolReferences and Literature

1. Raman J, et al. Am J Trop Med Hyg. 2010, 82(5):788-94.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Parasitic Compound Library NO PAINS Compound Library Inhibitor Library Anti-COVID-19 Compound Library Cell Cycle Compound Library ReFRAME Related Library Metabolism Compound Library

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Keywords

Sulfadoxine 2447-57-6 Autophagy Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism Microbiology/Virology Proteases/Proteasome DHFR HIV Protease Antibiotic Parasite HIV Human immunodeficiency virus inhibit Sulphadoxine Inhibitor inhibitor

 

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