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Alvimopan

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Purity:99.97%

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COA HPLC HNMR

Alvimopan

Catalog No. T1242Cas No. 156053-89-3

Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, this agent binds to mu-opioid receptors in the gut, thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.

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Pack Size	Price	Availability
1 mg	$45	In Stock
2 mg	$63	In Stock
5 mg	$90	In Stock
10 mg	$142	In Stock
25 mg	$268	In Stock
50 mg	$397	In Stock
100 mg	$589	In Stock
500 mg	$1,280	In Stock
1 mL x 10 mM (in DMSO)	$90	In Stock

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	424.53
Formula	C25H32N2O4
Cas No.	156053-89-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL(188.4 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3555 mL	11.7777 mL	23.5555 mL	117.7773 mL
5 mM	0.4711 mL	2.3555 mL	4.7111 mL	23.5555 mL
10 mM	0.2356 mL	1.1778 mL	2.3555 mL	11.7777 mL
20 mM	0.1178 mL	0.5889 mL	1.1778 mL	5.8889 mL
50 mM	0.0471 mL	0.2356 mL	0.4711 mL	2.3555 mL
100 mM	0.0236 mL	0.1178 mL	0.2356 mL	1.1778 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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