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BMS-582949 hydrochloride

Catalog No. T3462Cas No. 912806-16-7
Alias BMS-582949 HCl

The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).

BMS-582949 hydrochloride

BMS-582949 hydrochloride

Purity: 98.75%
Catalog No. T3462Alias BMS-582949 HClCas No. 912806-16-7
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
Pack SizePriceAvailabilityQuantity
1 mg$47In Stock
2 mg$67In Stock
5 mg$108In Stock
10 mg$172In Stock
25 mg$289In Stock
50 mg$463In Stock
100 mg$689In Stock
500 mg$1,430In Stock
1 mL x 10 mM (in DMSO)$119In Stock
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Purity:98.75%
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Product Introduction

Bioactivity
Description
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
Targets&IC50
p38α MAPK:13 nM
AliasBMS-582949 HCl
Chemical Properties
Molecular Weight442.95
FormulaC22H27ClN6O2
Cas No.912806-16-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (112.88 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2576 mL11.2880 mL22.5759 mL112.8796 mL
5 mM0.4515 mL2.2576 mL4.5152 mL22.5759 mL
10 mM0.2258 mL1.1288 mL2.2576 mL11.2880 mL
20 mM0.1129 mL0.5644 mL1.1288 mL5.6440 mL
50 mM0.0452 mL0.2258 mL0.4515 mL2.2576 mL
100 mM0.0226 mL0.1129 mL0.2258 mL1.1288 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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