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Broxyquinoline

🥰Excellent
Catalog No. T0701Cas No. 521-74-4
Alias Dibromohydroxyquinoline, 5,7-Dibromo-8-hydroxyquinoline

Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.

Broxyquinoline

Broxyquinoline

🥰Excellent
Purity: 99.1%
Catalog No. T0701Alias Dibromohydroxyquinoline, 5,7-Dibromo-8-hydroxyquinolineCas No. 521-74-4
Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.
Pack SizePriceAvailabilityQuantity
100 mg$30In Stock
500 mg$57In Stock
1 g$82In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.1%
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Product Introduction

Bioactivity
Description
Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.
In vivo
Broxyquinoline inhibits the in vitro activity of prolyl and asparaginyl hydroxylation of HIF-1α. Additionally, Broxyquinoline inhibits the binding of CpACBP1 to NBD-palmitoyl-CoA.
AliasDibromohydroxyquinoline, 5,7-Dibromo-8-hydroxyquinoline
Chemical Properties
Molecular Weight302.95
FormulaC9H5Br2NO
Cas No.521-74-4
SmilesOC1=C(Br)C=C(Br)C2=CC=CN=C12
Relative Density.2.052g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 10 mg/mL (33.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3009 mL16.5044 mL33.0087 mL165.0437 mL
5 mM0.6602 mL3.3009 mL6.6017 mL33.0087 mL
10 mM0.3301 mL1.6504 mL3.3009 mL16.5044 mL
20 mM0.1650 mL0.8252 mL1.6504 mL8.2522 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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