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Cedazuridine

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Catalog No. T26972Cas No. 1141397-80-9
Alias (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine

Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.

Cedazuridine

Cedazuridine

🥰Excellent
Purity: 99.46%
Catalog No. T26972Alias (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridineCas No. 1141397-80-9
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
Pack SizePriceAvailabilityQuantity
1 mg$50In Stock
5 mg$97In Stock
10 mg$155In Stock
25 mg$318In Stock
50 mg$479In Stock
1 mL x 10 mM (in DMSO)$119In Stock
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Purity:99.46%
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Product Introduction

Bioactivity
Description
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
In vivo
Oral Cedazuridine when combined with Azacitidine achieves successful tumor regression in both human cell line-derived xenograft transplantation experiment and patient-derived xenograft models[2].
Alias(4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine
Chemical Properties
Molecular Weight268.21
FormulaC9H14F2N2O5
Cas No.1141397-80-9
SmilesOC[C@H]1O[C@@H](N2CC[C@@H](O)NC2=O)C(F)(F)[C@@H]1O
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (186.42 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7284 mL18.6421 mL37.2842 mL186.4211 mL
5 mM0.7457 mL3.7284 mL7.4568 mL37.2842 mL
10 mM0.3728 mL1.8642 mL3.7284 mL18.6421 mL
20 mM0.1864 mL0.9321 mL1.8642 mL9.3211 mL
50 mM0.0746 mL0.3728 mL0.7457 mL3.7284 mL
100 mM0.0373 mL0.1864 mL0.3728 mL1.8642 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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