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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $38 | In Stock | |
100 mg | $54 | In Stock | |
200 mg | $63 | In Stock | |
500 mg | $107 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2. |
Alias | Dermovate, Clobetasol 17-propionate, CGP9555, Temovate, CCl 4725 |
Molecular Weight | 466.97 |
Formula | C25H32ClFO5 |
Cas No. | 25122-46-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 86 mg/mL (184.2 mM) Ethanol: 16 mg/mL (34.3 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
DMSO
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