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Dopexamine hydrochloride
🥰Excellent
Catalog No. T11318Cas No. 86484-91-5
Alias FPL60278AR
Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.
Dopexamine hydrochloride
🥰Excellent
Purity: 98.55%
Catalog No. T11318Alias FPL60278ARCas No. 86484-91-5
Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $48 | In Stock | |
| 2 mg | $68 | In Stock | |
| 5 mg | $113 | In Stock | |
| 10 mg | $178 | In Stock | |
| 25 mg | $372 | In Stock | |
| 50 mg | $556 | In Stock | |
| 100 mg | $783 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $126 | In Stock |
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Purity:98.55%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. |
| In vitro | Dopexamine, a dopamine analogue, stimulates β-adrenergic as well as dopamine 1 and 2 receptors, offering vasodilatory effects. It effectively mitigates the systemic inflammatory response triggered by endotoxin, including the release of cytokines, the expression of endothelial adhesion molecules, and oxidative stress, without significantly affecting systemic hemodynamics, such as blood pressure or stroke volume. Additionally, dopexamine possesses agonist activity at β2 and dopaminergic receptors, and at dosages that do not impact global hemodynamics or regional microvascular flow, it can diminish tissue leukocyte infiltration and confer protection against organ damage. |
| Alias | FPL60278AR |
| Molecular Weight | 429.42 |
| Formula | C22H34Cl2N2O2 |
| Cas No. | 86484-91-5 |
| Smiles | Cl.Cl.Oc1ccc(CCNCCCCCCNCCc2ccccc2)cc1O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (23.29 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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