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DOPEXAMINE
Catalog No. T8653Cas No. 86197-47-9
Dopexamine is a dopaminergic agonist
DOPEXAMINE
Catalog No. T8653Cas No. 86197-47-9
Dopexamine is a dopaminergic agonist
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $133 | In Stock | |
| 2 mg | $198 | In Stock | |
| 5 mg | $298 | In Stock | |
| 10 mg | $453 | In Stock | |
| 25 mg | $747 | In Stock | |
| 50 mg | $1,050 | In Stock | |
| 100 mg | $1,420 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $323 | In Stock |
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Purity:99.42%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Dopexamine is a dopaminergic agonist |
| In vivo | Dopexamine hydrochloride has interesting vasodilator properties, with marked intrinsic agonist activity at beta-2 adrenoreceptors and a lesser agonist activity at dopaminergic receptors (DA1 and DA2).?Dopexamine hydrochloride is responsible for an inhibition of neuronal re-uptake of catecholamines (uptake-1), producing an indirect stimulation of cardiac beta 1-receptors.?Dopexamine hydrochloride improves cardiac performance by a marked vasodilation and a mild inotropic activity.?The specific activity at dopaminergic receptors increases cerebral, myocardial, splanchnic and renal blood flows.?These haemodynamic effects are associated with an increase in diuresis and natriuresis.?These benefits are achieved without side effects such as an increased myocardial oxygen consumption, although induced tachycardia may be responsible for chest pain/anginae pain in patients with ischaemic heart disease[1]. |
| Molecular Weight | 356.5 |
| Formula | C22H32N2O2 |
| Cas No. | 86197-47-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/ml (154.28 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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