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Erythromycin ethylsuccinate

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Catalog No. T0474Cas No. 1264-62-6
Alias EES

Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.

Erythromycin ethylsuccinate

Erythromycin ethylsuccinate

🥰Excellent
Purity: 98%
Catalog No. T0474Alias EESCas No. 1264-62-6
Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.
Pack SizePriceAvailabilityQuantity
100 mg$35In Stock
200 mg$48In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98%
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Product Introduction

Bioactivity
Description
Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.
In vitro
It inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
AliasEES
Chemical Properties
Molecular Weight862.05
FormulaC43H75NO16
Cas No.1264-62-6
SmilesCCOC(=O)CCC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C
Relative Density.1.1417 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 158 mg/mL (183.3 mM)
DMSO: 158 mg/mL (183.3 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.1600 mL5.8001 mL11.6003 mL58.0013 mL
5 mM0.2320 mL1.1600 mL2.3201 mL11.6003 mL
10 mM0.1160 mL0.5800 mL1.1600 mL5.8001 mL
20 mM0.0580 mL0.2900 mL0.5800 mL2.9001 mL
50 mM0.0232 mL0.1160 mL0.2320 mL1.1600 mL
100 mM0.0116 mL0.0580 mL0.1160 mL0.5800 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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