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Femoxetine

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Catalog No. T68069Cas No. 59859-58-4

Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the production of high exercise capacity in mice.

Femoxetine

Femoxetine

🥰Excellent
Purity: 99.06%
Catalog No. T68069Cas No. 59859-58-4
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the production of high exercise capacity in mice.
Pack SizePriceAvailabilityQuantity
1 mg$126In Stock
5 mg$318In Stock
10 mg$460In Stock
25 mg$708In Stock
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Purity:99.06%
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Product Introduction

Bioactivity
Description
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the production of high exercise capacity in mice.
In vivo
In 11 patients, Femoxetine (300 mg; daily) decreased blood serotonin from 0.17 +/- 0.06 microgram/ml (mean +/- SD) to 0.06 +/- 0.02 microgram/ml. In 8 patients treated with 300 mg femoxetine daily for 12 weeks, 14C-serotonin uptake into platelets in vitro was reduced significantly. Unlike most drugs used in migraine prophylaxis, femoxetine did not influence platelet aggregation in vitro.[3]
Chemical Properties
Molecular Weight311.42
FormulaC20H25NO2
Cas No.59859-58-4
SmilesC(OC1=CC=C(OC)C=C1)[C@@H]2[C@H](CCN(C)C2)C3=CC=CC=C3
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (160.55 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2111 mL16.0555 mL32.1110 mL160.5549 mL
5 mM0.6422 mL3.2111 mL6.4222 mL32.1110 mL
10 mM0.3211 mL1.6055 mL3.2111 mL16.0555 mL
20 mM0.1606 mL0.8028 mL1.6055 mL8.0277 mL
50 mM0.0642 mL0.3211 mL0.6422 mL3.2111 mL
100 mM0.0321 mL0.1606 mL0.3211 mL1.6055 mL

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