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GDC-0623 (RG 7421) is a potent, ATP-uncompetitive MEK1 inhibitor with a Ki of 0.13 nM, currently in Phase 1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $48 | In Stock | |
2 mg | $67 | In Stock | |
5 mg | $122 | In Stock | |
10 mg | $197 | In Stock | |
25 mg | $295 | In Stock | |
50 mg | $388 | In Stock | |
100 mg | $645 | In Stock | |
1 mL x 10 mM (in DMSO) | $122 | In Stock |
Description | GDC-0623 (RG 7421) is a potent, ATP-uncompetitive MEK1 inhibitor with a Ki of 0.13 nM, currently in Phase 1. |
Targets&IC50 | MEK1:0.13 nM(ki) |
Alias | RG 7421, MEK inhibitor 1, GDC0623, G-868 |
Molecular Weight | 456.21 |
Formula | C16H14FIN4O3 |
Cas No. | 1168091-68-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 5 mg/mL (11 mM) DMSO: 91 mg/mL (198.82 mM), Heating is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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