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Indinavir sulfate
🥰Excellent
Catalog No. T5863Cas No. 157810-81-6
Alias MK-639 sulfate, L735524 sulfate
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
Indinavir sulfate
🥰Excellent
Purity: 100%
Catalog No. T5863Alias MK-639 sulfate, L735524 sulfateCas No. 157810-81-6
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $37 | In Stock | |
| 5 mg | $63 | In Stock | |
| 10 mg | $94 | In Stock | |
| 25 mg | $139 | In Stock | |
| 50 mg | $198 | In Stock | |
| 100 mg | $298 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. |
| Targets&IC50 | HIV-1:0.41 nM |
| In vitro | At low concentrations (0.0003-10?μmol/l) indinavir acts as a positive allosteric modulator (EC50?=?0.021?μmol/l), whereas at concentrations greater than 10?μmol/l (30-100?μmol/l) indinavir acts as an inhibitor of the α7-nicotinic acetylcholine receptor. |
| Alias | MK-639 sulfate, L735524 sulfate |
| Molecular Weight | 711.87 |
| Formula | C36H49N5O8S |
| Cas No. | 157810-81-6 |
| Smiles | OS(O)(=O)=O.CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (140.48 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
SARS-CoVSARSCoVSARS coronavirusPBMCMMPMK-639 SulfateMK639 SulfateMK-639MK639MK 639 SulfateMK 639Matrix metalloproteinasesL-735524 SulfateL735524 SulfateL-735524L735524L 735524 SulfateL 735524InhibitorinhibitIndinavir SulfateIndinavir sulfateIndinavirHuman immunodeficiency virusHuh7HIVProteaseHIV ProteaseHIVhepatocarcinomasCD4 T cellsApoptosis
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