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LY900009

🥰Excellent
Catalog No. T9015Cas No. 209984-68-9

LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.

LY900009

LY900009

🥰Excellent
Purity: 97.07%
Catalog No. T9015Cas No. 209984-68-9
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.
Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
5 mg$77In Stock
10 mg$121In Stock
25 mg$218In Stock
50 mg$323In Stock
100 mg$467In Stock
200 mg$655In Stock
1 mL x 10 mM (in DMSO)$94In Stock
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Purity:97.07%
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Product Introduction

Bioactivity
Description
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.
Chemical Properties
Molecular Weight409.48
FormulaC23H27N3O4
Cas No.209984-68-9
SmilesN(C([C@@H](NC([C@H](C(C)C)O)=O)C)=O)[C@H]1C=2C(C=3C(N(C)C1=O)=CC=CC3)=CC=CC2
Relative Density.1.27 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 11 mg/mL (26.86 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4421 mL12.2106 mL24.4212 mL122.1061 mL
5 mM0.4884 mL2.4421 mL4.8842 mL24.4212 mL
10 mM0.2442 mL1.2211 mL2.4421 mL12.2106 mL
20 mM0.1221 mL0.6105 mL1.2211 mL6.1053 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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