Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induced Aβ aggregation, displays significant antioxidant activity, and demonstrates substantial penetration through the blood-brain barrier (BBB). TM-10 holds promise as a potential treatment for Alzheimer’s disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
2 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 448.00 | |
10 mg | In stock | $ 658.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,890.00 |
Description | BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induced Aβ aggregation, displays significant antioxidant activity, and demonstrates substantial penetration through the blood-brain barrier (BBB). TM-10 holds promise as a potential treatment for Alzheimer’s disease. |
Targets&IC50 | BuChE:8.9 nM |
Synonyms | TM-10 |
Molecular Weight | 498.66 |
Formula | C32H38N2O3 |
CAS No. | 2313524-95-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.48 mg/mL (11 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BuChE-IN-TM-10 2313524-95-5 Neuroscience AChR TM 10 TM-10 TM10 inhibitor inhibit