Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 297.00 | |
25 mg | In stock | $ 490.00 | |
50 mg | In stock | $ 728.00 | |
100 mg | In stock | $ 987.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 178.00 |
Description | Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization. |
Targets&IC50 | Tubulin polymerization:0.52 μM |
In vitro | Crolibulin demonstrates notable cytotoxic effects on HT-29 cells, achieving an IC50 value of 0.52 μM[2]. It is effective against a range of experimental tumors and significantly inhibits mitosis during the G2/M phase[2]. |
Synonyms | EPC2407 |
Molecular Weight | 417.26 |
Formula | C18H17BrN4O3 |
CAS No. | 1000852-17-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (287.59 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Crolibulin 1000852-17-4 Cytoskeletal Signaling Microtubule Associated arrest anaplastic antineoplastic colchicine-binding antiproliferative EPC-2407 Apoptosis cancer cycle EPC 2407 thyroid site EPC2407 inhibit cell Inhibitor Microtubule/Tubulin inhibitor