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Methylthiouracil

🥰Excellent
Catalog No. T0304Cas No. 56-04-2
Alias NSC-9378, NSC-193526, MTU

Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.

Methylthiouracil

Methylthiouracil

🥰Excellent
Purity: 100%
Catalog No. T0304Alias NSC-9378, NSC-193526, MTUCas No. 56-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
Pack SizePriceAvailabilityQuantity
25 mg$40In Stock
50 mg$50In Stock
100 mg$74In Stock
200 mg$129In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
In vitro
Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.
AliasNSC-9378, NSC-193526, MTU
Chemical Properties
Molecular Weight142.18
FormulaC5H6N2OS
Cas No.56-04-2
SmilesCC1=CC(=O)NC(=S)N1
Relative Density.1.36 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 27 mg/mL (189.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.0333 mL35.1667 mL70.3334 mL351.6669 mL
5 mM1.4067 mL7.0333 mL14.0667 mL70.3334 mL
10 mM0.7033 mL3.5167 mL7.0333 mL35.1667 mL
20 mM0.3517 mL1.7583 mL3.5167 mL17.5833 mL
50 mM0.1407 mL0.7033 mL1.4067 mL7.0333 mL
100 mM0.0703 mL0.3517 mL0.7033 mL3.5167 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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