Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TBPB is an allosteric M1 mAChR agonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 118.00 | |
50 mg | In stock | $ 197.00 | |
100 mg | In stock | $ 369.00 | |
200 mg | In stock | $ 549.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | TBPB is an allosteric M1 mAChR agonist. |
Targets&IC50 | allosteric M1 mAChR:289 nM(ec50) |
Kinase Assay | in vitro kinase assay: MELK recombinant protein (0.4 μg) is mixed with 5 μg of each substrate in 20 μL of kinase buffer containing 30 mM Tris-HCl (pH), 10 mM DTT, 40 mM NaF, 10 mM MgCl2, 0.1 mM EGTA with 50 μM cold-ATP and 10 Ci of [γ-32P]ATP for 30 min at 30 °C. The reaction is terminated by addition of SDS sample buffer and boiled for 5 min prior to SDS-PAGE. The gel is dried and autoradiographed with intensifying screens at room temperature. OTSSP167 (final concentration of 10 nM) is dissolved in DMSO and added to kinase buffer before the incubation. |
Molecular Weight | 404.55 |
Formula | C25H32N4O |
CAS No. | 634616-95-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TBPB 634616-95-8 Neuroscience AChR inhibit Muscarinic acetylcholine receptor Inhibitor mAChR inhibitor