Home Tools
Log in
Cart

Tizoxanide

Catalog No. T2279   CAS 173903-47-4
Synonyms: Desacetyl-nitazoxanide, TIZ

Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Tizoxanide Chemical Structure
Tizoxanide, CAS 173903-47-4
Pack Size Availability Price/USD Quantity
5 mg In stock $ 46.00
10 mg In stock $ 72.00
25 mg In stock $ 148.00
50 mg In stock $ 233.00
100 mg In stock $ 346.00
1 mL * 10 mM (in DMSO) In stock $ 54.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 100%
Purity: 99.28%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
Synonyms Desacetyl-nitazoxanide, TIZ
Molecular Weight 265.25
Formula C10H7N3O4S
CAS No. 173903-47-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 38 mg/mL

TargetMolReferences and Literature

1. Korba BE, et al. Antiviral Res. 2008 Jan;77(1):56-63.2. Korba BE, et al. Antimicrob Agents ChemOthers. 2008 Nov;52(11):4069-71. 2. Ivanova L, Rausalu K, Žusinaite E, et al. 1, 3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors[J]. ACS Omega. 2021

TargetMolCitations

1. Ivanova L, Rausalu K, Žusinaite E, et al. 1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors. ACS Omega. 2021, 6(8): 5786-5794 2. Ivanova L, Rausalu K, Žusinaite E, et al. 1, 3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors. ACS Omega. 2021 Feb 17;6(8):5786-5794. doi: 10.1021/acsomega.0c06191. eCollection 2021 Mar 2.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library NO PAINS Compound Library FDA-Approved Drug Library Anti-Aging Compound Library Inhibitor Library Approved Drug Library Drug Repurposing Compound Library Anti-Bacterial Compound Library

Related Products

Related compounds with same targets
Didemnin B Hypericin SIRT1-IN-1 BF738735 Surfen dihydrochloride IND24 Capsorubin Brincidofovir

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tizoxanide 173903-47-4 Autophagy Immunology/Inflammation Microbiology/Virology Proteases/Proteasome Antiviral HIV Protease Antibacterial bacteria Human immunodeficiency virus Parasite AMPK HCV I kappa B kinase Nitazoxanide anaerobic IKK Desacetyl-nitazoxanide protozoa viruses Inhibitor HIV NF-κB IκB kinase HBV parasites Influenza Virus MAPK IKK-α Bacterial TIZ inhibit inhibitor

 

TargetMol